In Vitro Synergistic Activities of Tobramycin and Selected b-Lactams against 75 Gram-Negative Clinical Isolates
نویسندگان
چکیده
ROBERT C. OWENS, JR.,* MARY ANNE BANEVICIUS, DAVID P. NICOLAU, CHARLES H. NIGHTINGALE, AND RICHARD QUINTILIANI Department of Clinical Pharmacy Services, Medical Center of Delaware, Newark, Delaware 19718; School of Pharmacy, University of Maryland, Baltimore, Maryland 21201; Philadelphia College of Pharmacy and Science, Philadelphia, Pennsylvania 19104; and Department of Pharmacy Research, Office for Research, and Division of Infectious Diseases, Hartford Hospital, Hartford, Connecticut 06102
منابع مشابه
In vitro synergistic activities of tobramycin and selected beta-lactams against 75 gram-negative clinical isolates.
The microdilution checkerboard technique was utilized to distinguish synergistic activity between tobramycin and four beta-lactams: piperacillin-tazobactam, ticarcillin-clavulanate, ceftazidime, and ceftriaxone. Beta-lactam-aminoglycoside combinations were tested against 75 clinical isolates of Pseudomonas aeruginosa, Acinetobacter baumanii, Citrobacterfreundii, Serratia marcescens, and Enterob...
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